dembart/mlyzed

mlyzed scores a 2 on defensibility due to near-zero adoption (1 star, 1 fork) and significant age without maintenance (over 3 years old with zero velocity). The project appears to be a personal or lab-specific collection of scripts for analyzing molecular dynamics trajectories. The field of MD post-processing is already heavily consolidated around mature, high-performance libraries like MDAnalysis and MDTraj, which offer significantly more robust feature sets, performance optimizations, and community support. Frontier labs (OpenAI, Google) are unlikely to compete here as the niche is highly academic and domain-specific, but the project is essentially pre-displaced by existing open-source standards. There is no evidence of a novel algorithmic moat or unique data gravity that would prevent a user from simply using a more established library.